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Am Rev Respir Dis 1977;116:1031–7. 36. Tepper RS, Morgan WJ, Cota K, et al. Physiologic growth and development of the lung during the first year of life. Am Rev Respir Dis 1986;134:513–9. 37. Peat JK, Salome CM, Xuan W. On adjusting measurements of airway responsiveness for lung size and airway caliber. Am J Respir Crit Care Med 1996;154:870–5. 38. Sears MR, Burrows B, Flannery EM, et al. Atopy in childhood. I. Gender and allergen-related risks for development of hay fever and asthma. Clin Exp Allergy 1993;23:941–8.

Hattevig G, Kjellman B, Johansson SG, et al. Clinical symptoms and IgE responses to common food proteins in atopic and healthy children. Clin Allergy 1984;14:551–9. 9. Rowntree S, Cogswell JJ, Platts-Mills TAE, et al. Development of IgE and IgG antibodies to food and inhalant allergens in children at risk of allergic disease. Arch Dis Child 1985;60:727–35. 10. Prescott SL, Macaubas C, Smallacombe TB, et al. Development of allergen-specific T cell memory in atopic and normal children. Lancet 1999;353:196–200.

Filaggrin and cat exposure: Loss-of-function mutations in the gene encoding filaggrin (important to skin physical barrier) have been associated with the development of AD. 140 The effect of cat exposure was independent of allergic sensitization, and not observed with either dog ownership or mite allergen levels. Pharmacologic Intervention Several studies have attempted to determine if conventional therapy for allergy and asthma may be able to alter the natural course of the allergic march or to prevent persistent allergic disease and chronic asthma.

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AMPEX MM1200 Recorder - Problems and Solutions (broadcast)


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